Whether it’s fireworks, vet visits, car rides, or separation anxiety, stress affects dogs more than many pet parents realize. Some dogs tremble, bark excessively, hide, or even refuse food — all common signs of canine anxiety and emotional stress.
That’s where calming supplements for dogs can help. These vet-formulated calming chews, oils, and soft bites are made with gentle, natural ingredients like chamomile, L-theanine, melatonin, and hemp to support relaxation without sedation. They help dogs feel calmer, more secure, and better able to cope with everyday triggers.
We’ve handpicked some of the best calming supplements for dogs, trusted by thousands of dog owners for both daily anxiety relief and occasional use. Whether your dog is a nervous traveler, storm-phobic, or an anxious rescue, there’s a safe and effective option here to bring peace back into their day.
📦 Notes:
1. Product sizes and packaging may vary slightly between shopping sites. Always double-check before purchasing.
2. More items coming your way soon.
🌙 1. Zesty Paws Puppy Calming Bites – Turkey Flavor, 90 Soft Chews (157 g)
Quick Pick: Gentle, turkey-flavored calming chews with chamomile, L-theanine, and melatonin — perfect for easing puppy nerves without sedation.
– Function: Specially designed for puppies, these soft chews promote relaxation during stressful events like crate training, vet visits, or travel. The formula features calming botanicals and amino acids that support a balanced mood and restful sleep, while being gentle on developing bodies.
– Key Features:
• Contains organic chamomile and valerian root for natural calming support
• L-theanine and L-tryptophan promote serotonin production to reduce anxiety
• Includes melatonin for healthy sleep cycles without drowsy side effects
• Puppy-safe formula with no artificial flavors or synthetic preservatives
• Soft texture that’s easy for young dogs to chew and digest
– Best For:
• Puppies experiencing separation anxiety or nervousness
• Calming during thunderstorms, car rides, or first grooming sessions
• Encouraging restful sleep at night
• Daily support for high-energy or easily overstimulated puppies
– Key Ingredients: Organic chamomile, valerian root, L-theanine, L-tryptophan, melatonin
👉 Buy on 🔴 iHerb.sg
👉 Buy on 🔴 iHerb.com
🌙 2. Purina Pro Plan Veterinary Supplements FortiFlora Calming Care – 30 Sachets
Quick Pick: Clinically studied probiotic supplement that helps manage anxiety in dogs by supporting a healthy gut–brain connection.
– Function: Developed by Purina’s veterinary science team, Calming Care contains a unique probiotic strain (BL999) shown to promote calm behavior in dogs experiencing stress, separation anxiety, or environmental changes. It works by supporting the gut microbiome — an essential player in regulating mood and emotional stability.
– Key Features:
• Contains Bifidobacterium longum BL999, a probiotic clinically shown to help dogs remain calm
• Helps manage common anxiety triggers like separation, visitors, or changes in routine
• Easy-to-use powder sachets — mix into wet or dry food daily
• Recommended for daily use for best long-term results
• Backed by veterinary research and suitable for both dogs and cats
– Best For:
• Dogs with general anxiety or stress-related behaviors
• Dogs adjusting to new environments or routines
• Long-term calming support through gut health
• Pet owners looking for a vet-trusted, non-sedating solution
– Key Ingredients: Bifidobacterium longum BL999 (probiotic blend), liver flavor, maltodextrin
👉 Buy on 🔴 Shopee.sg
🌙 3. VetriScience Calm & Confident Chews – Soft Chews (Veterinarian-Formulated) (Various Flavors and Sizes Available)
Quick Pick: Non-drowsy calming chews made with clinically studied Colostrum Calming Complex and L-theanine to support relaxed behavior during stressful events.
– Function: VetriScience Calm & Confident is designed to help dogs maintain emotional balance in high-stress situations such as thunderstorms, vet visits, car rides, or being left alone. It works by supporting the nervous system with natural amino acids and bioactive proteins that promote calm without sedation.
– Key Features:
• Contains Colostrum Calming Complex® Biopeptide Blend clinically shown to support relaxation
• Includes L-theanine (Suntheanine®) to help balance mood and reduce anxiety
• Non-drowsy formula helps maintain alertness and calmness together
• Duck-flavored soft chews that are easy to give and well accepted by dogs
• Suitable for daily use or occasional stressful events
– Best For:
• Dogs with noise phobia (e.g., thunderstorms, fireworks)
• Separation anxiety or travel-related stress
• Visits to the vet or groomer
• Dogs who become overstimulated in busy environments
– Key Ingredients: Colostrum Calming Complex® Biopeptide Blend, L-theanine (Suntheanine®), thiamine (vitamin B1)
👉 Buy on 🔴 Amazon.sg
👉 Buy on 🔴 Amazon.com
🌙 4. Fera Pets Calming Support Powder – 60 Servings
Quick Pick: Clean-label calming powder made with organic botanicals and amino acids to support relaxation, emotional balance, and healthy sleep in both dogs and cats.
– Function: This vet-developed calming powder blends organic herbs with key amino acids to help soothe nervousness, reduce restlessness, and promote calm behavior without sedation. Ideal for multi-pet households, it supports a balanced mood during stressful events like travel, thunderstorms, or separation.
– Key Features:
• Made with organic hemp seed, valerian root, L-theanine, and GABA for natural calming
• Includes organic chamomile, passion flower, and ginger for gentle stress relief
• Clean, vegan formula — no fillers, soy, corn, gluten, or artificial preservatives
• Versatile powder format — easy to mix into wet or dry food
• Suitable for both dogs and cats; 60 servings per container
– Best For:
• Dogs or cats with general anxiety or hyperactivity
• Multi-pet homes needing a shared calming solution
• Pets sensitive to chews or pills
• Daily mood support and occasional stress triggers
– Key Ingredients: Organic hemp seed, L-theanine, valerian root, GABA, organic chamomile, passion flower, ginger root
👉 Buy on 🔴 Shopee.sg
🌙 5. Life Extension DOG Stress & Behavior – Bacon‑Flavor 120 Soft Chews (~480 g)
Quick Pick: From the science-first team at Life Extension—this high-quality, veterinarian-formulated chew combines L‑theanine and melatonin for clean, proven calming support.
– Function: Designed to promote calm behavior and support a healthy stress response in dogs during thunderstorms, travel, separation, or changes in routine. The formula uses melatonin (1 mg) and L‑theanine (50 mg per chew) to help your dog relax and stay content without sedation. It’s made in the USA using rigorous quality control.
– Key Features:
• Premium formulation with L‑theanine and melatonin clinically shown to ease stress
• Delicious bacon‑flavored soft chews that are dog-friendly and easy to serve
• No artificial flavors or colors; non-GMO, gluten‑free formula
• Vet-backed supplement from a trusted brand known for research and purity
– Best For:
• Dogs showing anxiety before bedtime or during stressful events
• Managing reactivity to fireworks, thunderstorms, or being left alone
• Owners who prefer a science-grade, non-prescription calming solution
– Key Ingredients: L‑theanine (50 mg), melatonin (1 mg), bacon flavor, chickpea flour, canola oil, pork liver, glycerin, tapioca flour, sunflower lecithin, guar gum, tocopherols, sorbic acid
👉 Buy on 🔴 iHerb.sg
👉 Buy on 🔴 iHerb.com
🌙 6. VetriScience® Composure™ Long Lasting Calming Supplement for Dogs (50 Chews)
Quick Pick: Long-lasting calming chews with clinically proven ingredients that soothe stress for up to 8 hours — ideal for anxious or overactive dogs.
Function: Advanced calming support for dogs facing ongoing anxiety, environmental stress, or overexcitement.
Key Features:
– Clinically proven to begin working in as little as 30 minutes
– Effects last up to 8 hours per chew
– Includes patented colostrum complex and Shoden® Ashwagandha
– Ideal for dogs with separation anxiety, noise reactivity, or vet/travel stress
– Recommended by veterinarians and made in the USA
Best For: Dogs with moderate to severe anxiety, dogs left alone during the day, multi-dog homes, rescue dogs adjusting to new environments
Key Ingredients: Colostrum Calming Complex®, L-theanine (Suntheanine®), Thiamine (Vitamin B1), Shoden® Ashwagandha
👉 Buy on 🔴 Shopee.sg
🌙 7. Zesty Paws Ancient Elements Calming Bites – Bison Flavor, 90 Soft Chews
Quick Pick: Calming chews with a unique ancient grain base and clinically studied active ingredients for gentle, all-ages support.
– Function: Designed to help dogs stay calm during daily stressors—separation, noise sensitivity, travel, storms—using a blend that supports composure and reduced tension.
– Key Features:
• Ancient grain blend (quinoa, millet, amaranth, sorghum) provides natural nutrition and digestibility
• Suntheanine® (clinically studied L‑theanine) promotes relaxation
• Sensoril® Ashwagandha supports stress-adjustment and calm mood
• Includes hemp seed powder (source of stearidonic acid), valerian root, melatonin for holistic calm
• No artificial flavors, colors, or preservatives; NASC-quality certified; made in the USA
– Best For:
• Dogs needing daily composure and emotional balance
• All ages, including senior dogs with sensitivities to rich ingredients
• Owners focusing on whole‑food, clean‑label ingredients with proven calming actives
– Key Ingredients: Quinoa, millet, amaranth, sorghum, Hemp Seed Powder, Suntheanine® (L‑theanine), Sensoril® (Ashwagandha), Valerian Root, Melatonin, Passionflower, Lemon Balm, Ginger Root
👉 Buy on 🔴 iHerb.com
🌙 8. Australian Pet Organics Calm Support – Certified Organic Powder (240 g/480 g)
Quick Pick: Organic Mood Support Powder with Brain-Boosting Botanicals
– Function: Supports natural mood balance and emotional calm in dogs of all ages. Combines mood-leveling herbs and brain-nourishing foods to help manage anxiety with everyday use.
– Key Features:
• Certified organic ingredients like Sprouted Rice Protein, St John’s Wort, Broccoli Powder, Almond Meal, and Green-Lipped Mussel Powder
• Supaw™ formula provides natural choline from sunflower lecithin for cognitive support
• Rich in antioxidants (Vitamin E & C), magnesium, tryptophan, and MCTs from coconut flour
• Free from artificial preservatives, additives, soy, wheat, or fillers • Made in Australia; suitable for puppies, adults, and seniors
• Scoop powder easily mixed into daily food — gentle for sensitive stomachs
– Best For:
• Dogs with mild anxiety, nervousness, or stress reactivity
• Daily emotional support and cognitive wellness in multi-dog households
• Owners preferring certified-organic, whole-food botanical blends
• Puppies and seniors who need gentle nutrition-backed mood support
– Key Ingredients: Sprouted Rice Protein, Coconut Flour, St John’s Wort Powder, Sunflower Lecithin Powder, Almond Meal, Oat Flour, Broccoli Powder, Apple Powder, Beef Bone Broth Powder, Green Lipped Mussel Powder
👉 Buy on 🔴 Shopee.sg
📝 Bonus Tip:
For better results, give calming supplements 30 to 60 minutes before a known stress trigger, like a vet visit or thunderstorm. Pair it with a quiet space, soothing music, or a favorite toy to help your dog feel even more secure.
❓ Q&A
Q: Can I give calming supplements every day?
A: Many are designed for daily use, but always check the label. Some are better suited for occasional support during stressful events.
Q: Are calming supplements safe for all dogs?
A: Most premium calming chews use natural ingredients like L-theanine and chamomile, but it’s still best to consult your vet — especially if your dog is on medication or has a health condition.
Q: Will these make my dog drowsy?
A: Not typically. High-quality calming supplements aim to ease anxiety without full sedation, so your dog stays relaxed but alert.
🐶 Final Thoughts
While options are still limited in the premium calming supplement space, the products listed here are among the best available. They’re backed by reputable brands, clean ingredients, and solid customer trust. If your dog struggles with stress, these calming aids might just make everyone’s day a little more peaceful.
Stay tuned — more wellness categories are coming soon to help your dog live their happiest, healthiest life.