Just like humans, dogs rely on healthy kidneys and a strong liver to filter toxins, process nutrients, and stay energized. But over time, these vital organs can weaken — especially in senior dogs or those on long-term medications.
That’s where dog kidney and liver supplements come in. These vet-formulated chews, powders, and capsules are made with powerful ingredients like milk thistle, cranberry extract, dandelion root, and antioxidants to help detoxify the liver, support kidney function, and promote better urinary health.
If your dog is aging, recovering from illness, or just needs extra support for organ health, these supplements offer a safe, natural way to boost their well-being — one daily dose at a time.
Notes:
1. Packaging design and sizing may vary slightly depending on which online store you purchase from. Always check before buying.
2. More listings will be added soon. Stay tuned!
🌿 1. VetriScience Vetri‑Liver Canine Chews – Chicken Liver Flavor, 60 Bite‑Sized Chews
Quick Pick: Vet-formulated liver support chews with 15 synergistic ingredients to support both Phase I & Phase II detox pathways.
– Function: Designed to support natural liver detoxification, promote glutathione and SAMe production, and help maintain healthy liver function and normal enzyme levels in dogs of all ages.
– Key Features:
• packs milk thistle, turmeric, artichoke leaf, DMG, N‑acetyl cysteine, whey protein isolate, vitamins B & E, zinc and folic acid to promote liver cell health and antioxidant pathways
• supports metabolic processes and bile production for waste elimination
• veterinarians recommend daily use; made in the USA under NASC quality standards
• soft chew format with palatability effort, although some dogs are sensitive to strong odor
– Best For:
• Dogs with liver enzyme elevations, recovering from mild liver strain or poor nutrition
• Seniors on long-term medication or post-illness detox support
• Wellness routines including periodic detox needs or elevated toxin exposure
– Key Ingredients: Whey protein isolate, Betaine (DMG), Turmeric extract, Milk thistle extract (silymarin), N‑acetyl cysteine, Artichoke leaf extract, Vitamin E, B vitamins (B1, B2, B6, Folate, B12), Zinc, Folic acid
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🌿 2. ThorneVet Kidney Support Formula – Soft Chews, 90-count
Quick Pick: Science-backed kidney support chews for dogs and cats, blending traditional botanicals and antioxidants to promote renal filtration and reduce oxidative stress.
– Function: Supports healthy kidney filtration, enhances blood flow to renal tissue, and reduces toxin burden on the kidneys.
– Key Features:
• Promotes optimal filtration with Rehmannia Root & Astragalus Root
• Nettle Seed supports tissue repair and regeneration
• Reishi and Cordyceps nourish kidney tissue and immunity
• CoQ10 & Astaxanthin deliver powerful antioxidant protection
• Chitosan helps bind phosphorus and protect kidney integrity
– Best For:
• Pets with early-stage kidney concerns
• Aging cats or dogs
• Environmental toxin exposure
• Long-term renal support
– Key Ingredients: Prepared Rehmannia Root, Astragalus Root (organic), Nettle Seed, Reishi Mushroom Extract, Cordyceps Mushroom Extract, Chitosan, Coenzyme Q10, Astaxanthin
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🌿 3. Zesty Paws Liver Support Bites – Chicken Flavor, 90 Soft Chews
Quick Pick: Grain‑free soft chews with standardized milk thistle, curcumin, NAC and dandelion for daily liver detox support.
– Function: Designed to support normal liver detoxification, antioxidant protection, bile production, and healthy enzyme levels in dogs at risk of liver strain.
– Key Features:
• Contains Silactive™ milk thistle extract (110 mg per chew) to support liver health and detox pathways
• Includes Qmin+™ curcumin (95% curcuminoids) with BioPerine® for enhanced absorption and joint support
• N‑Acetyl Cysteine (75 mg), choline bitartrate (50 mg), and dandelion root help support antioxidant levels and healthy liver function
• Made in the USA, grain‑free, and flavored naturally with chicken; no artificial preservatives
• Pet owners report support for elevated liver enzymes and improved energy in clinical use
– Best For: Dogs with elevated liver enzymes, chronic medication use, recovery from liver stress, or ongoing wellness routines needing gentle support.
– Key Ingredients: Milk Thistle (Silactive™), Curcumin (Qmin+™), BioPerine®, N‑Acetyl Cysteine, Choline Bitartrate, Dandelion Root
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🌿4. VetriScience Kidney Health – Chewable Tablets (60 ct)
Quick Pick: Vet‑recommended kidney support chews blending traditional botanic extracts with essential vitamins and omega fatty acids for complete renal wellness.
– Function: Forms a synergistic support for renal circulation, detoxification, fluid/mineral balance, and immune/oxidative defense to help maintain normal kidney filtration and function.
– Key Features:
• Contains Astragalus root, Rehmannia, Nettle leaf, and Cordyceps to improve kidney blood flow and filtration
• Includes EPA & DHA Omega‑3 fatty acids, DMG, and essential B vitamins to support metabolic detox pathways and energy
• Made in the USA in SQF‑certified, FDA-registered facilities; holds the NASC quality seal
• Chicken-liver flavored soft chews, palatability tested for easy daily use
– Best For:
• Senior dogs or pets with early-stage kidney stress
• Dogs with minor elevations in renal enzymes or mild chronic stress
• Long-term kidney wellness routines and toxin protection
– Key Ingredients: Astragalus root powder, Rehmannia root extract, Nettle leaf extract, Cordyceps extract, Lecithin, L‑Arginine, DMG, EPA & DHA, Inositol, Vitamins B1/B2/B6/B12, Choline, Folic acid
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🌿 5. Fera Pets Liver Support for Dogs & Cats – Chicken Bone Broth Powder (60 servings)
Quick Pick: Vet-formulated powder blend with milk thistle, turmeric curcumin, NAC, and BioPerine to promote liver detox, oxidative balance, and healthy enzyme levels.
– Function: Supports natural liver detoxification, antioxidant protection, and digestion while also maintaining healthy blood sugar, immune, and hormone synthesis processes.
– Key Features:
• Milk thistle extract (150 mg) provides antioxidative and liver-regenerating support
• Turmeric Curcumin C3 Complex (75 mg) enhanced with BioPerine for better absorption
• Includes N-Acetyl-L-Cysteine (50 mg), Vitamins C & E, Choline, DMG, zinc, burdock and dandelion root for full botanical detox support
• Certified vet-formulated and third-party tested; made in the USA; no artificial additives
• Easy to mix into food with included scoop — gentle for dogs and cats with sensitive digestion
– Best For:
• Pets recovering from liver stress, long-term medication use, elevated liver enzymes, toxin exposure, aging or rescue sensitives
– Key Ingredients: Milk Thistle Extract, Turmeric Curcumin C3 Complex, BioPerine (Black Pepper), N-Acetyl-L-Cysteine, Choline, Dimethylglycine (DMG), Vitamin C, Vitamin E, Zinc, Artichoke Leaf, Burdock Root, Dandelion Root
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🌿 6. Bark & Whiskers Detox Support – Liver & Kidney Powder (52.3 g / ~96 scoops)
Quick Pick: Veterinarian-developed support powder with 13 potent botanicals and antioxidants to protect and detoxify both liver and kidneys.
– Function: Supports normal detoxification processes, promotes healthy liver and kidney function, and helps neutralize environmental toxins in dogs and cats.
– Key Features:
• Contains Japanese Knotweed (Resveratrol), Milk Thistle extract, Chlorella, Curcumin phytosome complex, Dandelion leaf, Glycine, NAC, Phosphatidylcholine, SOD, Taurine, Schisandra, Organic Green Tea extract (decaf), and L‑Glutathione
• Suitable for daily use as maintenance or short-term detox after toxin exposures (like medications or pollutants)
• Free from GMOs, gluten, and soy; made in the USA under veterinarian guidance
• Easy-to-dose powder with scoop sizes based on pet weight; gentle when mixed into food
– Best For:
• Cats or dogs undergoing environmental/toxin exposure, on long-term medication
• Seniors with compromised organ health
• Preventative daily organ support for overall wellness
– Key Ingredients: Japanese Knotweed (Resveratrol), Organic Milk Thistle Seed Extract, Organic Chlorella, Curcumin Phytosome Complex, Organic Dandelion Leaf, Glycine, N‑Acetyl L‑Cysteine (NAC), Phosphatidylcholine, Superoxide Dismutase (SOD), Taurine, Organic Schisandra Extract, Organic Green Tea Extract, L‑Glutathione
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🌿 7. Rx Vitamins Hepato Support – 100mg Milk Thistle Capsules, 90 ct.
Quick Pick: Professional-grade liver supplement with high-potency milk thistle and antioxidant liver cofactors, trusted by vets.
– Function: Supports liver detoxification, protects liver cells, and promotes healthy enzyme levels in dogs and cats.
– Key Features:
• Formulated by veterinarians with standardized milk thistle (80% silymarin, 30% silybinin)
• Includes antioxidant and liver-supportive nutrients: alpha-lipoic acid, inositol, choline, B-complex vitamins, DL-methionine
• Ideal for pets with elevated liver enzymes, aging dogs, or those on long-term medications
• Capsule form can be given directly or opened and mixed with food
– Best For:
• Dogs and cats needing detox or liver protection support
• Senior pets or those recovering from illness or medications
• Pets with high ALT/AST or other abnormal liver values
– Key Ingredients: Milk thistle extract (standardized), Alpha-lipoic acid, Inositol, Choline, DL-methionine, Vitamin B-complex
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🌿 8. Azovast Kidney Support Powder – 60 Servings, USA Made (Available in Various Sizes and Capsule type)
Quick Pick: Advanced kidney support powder with patented herbal blend and gut-friendly probiotics for early-stage or aging dogs.
– Function: Formulated to support healthy kidney function, promote optimal blood filtration, and reduce toxin accumulation through renal and intestinal pathways.
– Key Features:
• Contains AstraGin® (Panax notoginseng + Astragalus) to support nutrient absorption and kidney cell regeneration
• Includes inulin and microencapsulated probiotics for gut barrier support and uremic toxin reduction
• Manufactured in a GMP-certified USA facility with high safety and potency standards
• Tasteless, easy-mix powder ideal for dogs with appetite loss or pill fatigue
– Best For:
• Dogs with early-stage kidney disease, age-related renal decline, or chronic kidney issues
• Dogs recovering from urinary tract infections or dehydration-related kidney stress
• Dogs requiring ongoing renal health support with holistic and gentle ingredients
– Key Ingredients: AstraGin® (Panax notoginseng, Astragalus), Inulin, Microencapsulated Probiotics, Maltodextrin, Natural Flavor
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🌿 9. Natural Dog Company Liver & Kidney for Dogs – All Ages, 90 Soft Chewable Bites
Quick Pick: Turkey-flavored chews with milk thistle, curcumin, NAC, and apple cider vinegar for balanced liver and kidney support.
– Function: Supports natural detox for liver and kidneys, promotes healthy enzyme levels, and helps reduce toxin buildup for overall vitality.
– Key Features:
• Contains milk thistle extract and N‑acetyl cysteine for antioxidant protection and liver cell regeneration
• Includes curcumin and dandelion root to support kidney function and reduce inflammation
• Apple cider vinegar and choline bitartrate help promote digestion and metabolic balance
• Veterinarian-formulated and made with clean-label ingredients; no artificial additives
• Naturally flavored turkey bites designed for all life stages, including seniors
– Best For:
• Dogs needing gentle organ detox support due to age, medications, or environmental exposure
• Balanced daily maintenance in multi-dog households
• Pets with mild elevation in liver enzymes or slight kidney strain
– Key Ingredients: Milk Thistle Extract, Curcumin, N‑Acetyl Cysteine, Dandelion Root, Choline Bitartrate, Apple Cider Vinegar
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🌿 10. Fera Pets Kidney Support for Dogs – Proprietary Kidney-Probiotic Blend (60 g powder)
Quick Pick: Vet-formulated kidney supplement combining Eastern botanical medicine with a clinically studied kidney-health probiotic blend, designed for daily renal maintenance.
– Function: Promotes healthy kidney filtration, supports balanced fluid systems, and aids natural detoxification through both herbals and gut–kidney axis support.
– Key Features:
• Formulated with Astragalus root, Rehmannia root extract, and Cordyceps mushroom for traditional renal support
• Includes Chitosan to bind excess phosphorus and support detox pathways
• Contains SYNTEK® Kidney Health Probiotic Blend (5 billion CFU of Lactiplantibacillus plantarum MFM 30‑3 & Lacticaseibacillus paracasei MFM 18) for antioxidant and toxin-management benefits
• Veterinarian-created and NASC-certified; made in the USA in GMP/FDA-registered facility
• Easy-to-use powder with included scoop for long-term feeding or detox support
– Best For:
• Dogs with early-stage kidney concerns or mild elevations in renal markers
• Older dogs or those on long-term medications or toxin exposures
• Wellness routines focused on kidney health maintenance
– Key Ingredients: Organic Astragalus root powder, Organic Cordyceps, Rehmannia root extract, Chitosan, SYNTEK® Probiotic Kidney–Gut Blend (L. plantarum MFM 30‑3, L. paracasei MFM 18)
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🌿 11. NephroMax Synbiotic Capsules – Kidney Support (120 Caps)
Quick Pick: Advanced synbiotic kidney supplement combining probiotic strains and prebiotics to support healthy kidney filtration, reduce toxin load, and support gut–kidney detoxification.
– Function: Helps reduce stress on the kidneys by metabolizing nitrogenous waste, improving intestinal barrier health, and enhancing renal filtration through the gut–kidney axis.
– Key Features:
• Proprietary blend of pre- and probiotics (4 probiotic strains + 2 prebiotics) supports toxin breakdown and waste elimination
• Shelf-stable capsules require no refrigeration — convenient for long-term use
• Promotes gut microbiota balance and reduces uremic load on kidneys
• Suitable for pets of all ages, breeds, and kidney risk levels
– Best For:
• Pets with early-stage kidney decline or mild elevations in BUN/creatinine
• Senior dogs or cats exposed to toxins or medications
• Owners seeking gentle, microbiome-aware renal support for long-term wellness
– Key Ingredients: Proprietary probiotic blend (e.g. S. thermophilus, L. acidophilus, B. longum strains), inulin, xylo-oligosaccharide
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🧪 12. Rx Vitamins Rx Renal Canine – Kidney Support Capsules (120 Caps)
Quick Pick: Clinical-strength kidney support formula developed by veterinarians, featuring synergistic herbal extracts and nutraceuticals to support renal health and function.
– Function: Helps maintain kidney function by promoting healthy circulation, antioxidant protection, and normal detox pathways in dogs with early to moderate renal stress.
– Key Features:
• Formulated with milk thistle, cordyceps, and green tea extract for antioxidant and anti-inflammatory benefits
• Includes vitamin B6 and astragalus root to help manage oxidative stress and support renal filtration
• Capsule format ensures accurate dosing; can be opened and sprinkled over food
• Designed by veterinary professionals for use in wellness or alongside renal diets
– Best For:
• Dogs with early-stage kidney disease or aging-related renal decline
• Pets on long-term medication or prescription diets needing added support
• Holistic kidney maintenance for breeds prone to kidney issues
– Key Ingredients: Milk thistle extract (silymarin), Cordyceps sinensis, Green tea extract (EGCG), Astragalus root, Vitamin B6
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🌟 Bonus Tips: Supporting Your Dog’s Kidney & Liver Health Naturally
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🥣 Hydration is key: Always ensure your dog has access to fresh, clean water. Proper hydration helps flush toxins from the kidneys and supports healthy liver function.
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🐟 Feed a liver- and kidney-friendly diet: Opt for high-quality food that’s lower in phosphorus and sodium, with limited additives or artificial ingredients.
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🍀 Add antioxidant-rich foods: Blueberries, broccoli, and turmeric (in safe, dog-appropriate amounts) may help protect liver cells and reduce oxidative stress.
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🚶♂️ Keep your dog active: Gentle exercise supports circulation and organ function—just tailor the intensity to your dog’s age and condition.
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💊 Use supplements as a support, not a cure: These products aid organ health but should never replace veterinary care for dogs with diagnosed liver or kidney conditions.
❓ Frequently Asked Questions
Q: Can I give liver and kidney supplements to healthy dogs?
A: Yes! Many supplements are formulated for both preventative and supportive care. Dogs exposed to medications, environmental toxins, or processed foods can benefit from occasional detox support.
Q: How long does it take to see results from kidney or liver supplements?
A: While some ingredients may start supporting cellular health within days, noticeable improvements typically take 2–4 weeks of consistent use, depending on your dog’s condition.
Q: Are these supplements safe for senior dogs?
A: Absolutely. In fact, aging dogs often benefit most from liver and kidney support, especially if they’ve been on long-term medications or show early signs of decline.
Q: Can I use these supplements alongside prescription meds?
A: Most natural supplements are safe when used with vet-prescribed treatments, but it’s essential to check with your veterinarian to avoid interactions—especially with herbs like milk thistle or turmeric.
🐾 Final Thoughts: Give Their Vital Organs the Love They Deserve
Your dog’s kidneys and liver work tirelessly behind the scenes—filtering waste, metabolizing nutrients, and keeping their entire system running smoothly. Supporting these vital organs with high-quality supplements isn’t just smart; it’s a loving investment in their long-term health.
Whether your dog is recovering from illness, managing age-related decline, or simply living their best zoomie life, a carefully chosen supplement can make all the difference.